C14orf93

Gene Information

Official Symbol: C14orf93
Official Name: chromosome 14 open reading frame 93
Aliases and Previous Symbols: N/A
Entrez ID: 60686
UniProt: Q9H972
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Atovaquone 15μM R08 exp451	-1.75
A-769662 20μM R07 exp331	1.71
Dimethyloxaloylglycine 100μM R05 exp229	1.73
GSK-J4 1-1.25μM to day4 R07 exp363	1.74
Wortmannin 5μM R00 exp38	1.76
Chlorpromazine 10μM R07 exp344	1.85
Vinorelbine 0.001μM R05 exp249	1.86
Metformin 100 to 150μM on day4 R04 exp170	1.89
Taxol 0.002μM R01 exp54	1.95
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	2
Nicotinamide 2000μM R01 exp50	2

Gene	Correlation
VASN	0.622
TCEB3CL2	0.587
COPG1	0.578
POLR2J3	0.576
TBC1D3H	0.572
TFIP11	0.571
TBC1D3G	0.569
C1QTNF9B	0.563
CHD4	0.561
CBWD3	0.561
GOLGA8O	0.556
SLC4A1	0.554
TBC1D3C	0.553
MYO1H	0.55
NPIPB5	0.549
CBWD5	0.545
DTL	0.545
MT1E	0.544
CDC6	0.543
RBBP5	0.543
TICRR	0.541
TCEB3C	0.54
PSAP	0.537
SUPT5H	0.536
RPL35	0.532
ORC1	0.531
MDM2	0.529
AAMP	0.528
CBWD6	0.528
RANBP2	0.525
TBC1D3I	0.523
TBC1D3K	0.523
TBC1D3L	0.523
TBC1D3E	0.523
AQR	0.523
PSMB4	0.522
COPE	0.522
INTS5	0.522
COPA	0.52
SNRPA1	0.519
PSMB2	0.518
PSMD11	0.518
AKIRIN2	0.517
DISP2	0.517
TCEB3CL	0.516
SUPT6H	0.514
SF3A1	0.514
CCDC64B	0.514
PWP2	0.513
S1PR4	0.512
RPS2	0.512
TBC1D3F	0.51
MED17	0.51
TWISTNB	0.51
CCNA2	0.508
TBC1D3	0.508
PSMC6	0.508
NUP160	0.506
HAP1	0.506
CWC22	0.505
PAF1	0.505
PSMD3	0.504
PRIM1	0.503
EGR2	0.503
RPS5	0.5
RAD51	0.5
HIST2H3A	0.5
HIST2H3C	0.499
RAD21	0.498
RFXANK	0.498
CDC73	0.498
HIST2H2BF	0.498
WDR87	0.498
FBXW9	0.497
MYT1L	0.497
STIL	0.496
ZNF106	0.496
PSMC5	0.494
TRIM52	0.493
RRP7A	0.493
EIF4A3	0.492
NDC80	0.49
EXOSC9	0.489
KCTD17	0.489
CDCA3	0.488
NUPL1	0.487
POLR2F	0.486
DOCK6	0.486
POLA2	0.486
PSMC1	0.486
OR10G3	0.485
HIST1H4B	0.484
PAN2	0.484
RRN3	0.484
DDTL	0.483
APRT	0.483
SSH2	0.482
FAM25B	0.482
CHMP2A	0.482
ORC6	0.482
PLK1	0.481
BYSL	0.48
PAN3	0.48
PSMD6	0.48
RPSA	0.48
TYMS	0.478
RRM1	0.476
COL2A1	0.475
PLK4	0.475
SEC13	0.475
GOLGA8R	0.475
NDC1	0.475
FAM160A1	0.474
PDE4DIP	0.473
AAAS	0.472
CKAP5	0.471
ZFAND5	0.471
ZNF574	0.471
MYH2	0.471
KIF3C	0.471
IK	0.47
FBL	0.47
KRT78	0.47
PSMA6	0.47
SLC6A17	0.469
LRR1	0.469
RPS12	0.469
PSMD1	0.468
CCDC94	0.468
EBNA1BP2	0.468
PSMC2	0.467
RPL34	0.467
NBPF10	0.467
MYO18A	0.466
ABHD8	0.466
DDX56	0.464
RBM39	0.464
EXOSC5	0.464
ZNF219	0.461
NUP85	0.461
COPZ1	0.461
MCOLN1	0.461
NOL10	0.461
RPS3A	0.461
NUP155	0.46
TAF15	0.46
PSMD2	0.46
UTP3	0.459
TPX2	0.458
CEP192	0.458
PLA2G4F	0.458
LAD1	0.457
ANKLE2	0.457
VPS28	0.457
GOLGA6L3	0.457
PIGS	0.456
NUP54	0.456
RPS9	0.455
MED12	0.455
MSH5	0.453
POLE	0.453
COPB2	0.453
NOP16	0.452
PRMT8	0.451
NUP205	0.449
AHCTF1	0.449
ZNF655	0.448
RFFL	0.448
NPIPB8	0.448
SF3B3	0.447
SYT9	0.447
NSF	0.447
GAR1	0.447
LIPE	0.447
SPRR2B	0.447
SF3A2	0.446
GOLGA6A	0.446
RPL6	0.446
RPS19	0.444
RPL14	0.443
MPHOSPH10	0.443
SRSF1	0.443
GOLGA6L4	0.443
GPRIN2	0.443
PCF11	0.443
TIMELESS	0.443
CMYA5	0.442
MED29	0.442
POLA1	0.442
RNF4	0.442
CGB2	0.442
SF3A3	0.442
ATP6V1C1	0.441
USP35	0.441
INTS6	0.44
RPS14	0.44
PSMB1	0.44
C3orf17	0.44
GON4L	0.44
CCDC116	0.439
SAP30BP	0.439
ELMOD3	0.438
CNOT1	0.438
FAM86B2	0.437
CHAF1A	0.436
POLR1A	0.436
UPF1	0.435
OGFR	0.435
RPS7	0.434
SMG7	0.433
EXD1	0.433
RILPL1	0.433
ACSF2	0.432
SPRR2A	0.432
URB2	0.431
KIAA0947	0.431
ATP6V0B	0.43
DDX47	0.429
PSMD7	0.429
RNPC3	0.429
ZNF513	0.429
HIST1H2BE	0.429
FAM20A	0.428
GOLGA8K	0.428
CTR9	0.427
PSMB3	0.425
RPS28	0.425
NAPA	0.425
SFPQ	0.425
COPB1	0.424
RPS20	0.423
UTP20	0.423
FBXO5	0.423
UBAP1	0.422
TSG101	0.421
DNM2	0.421
ISCU	0.421
RPL10A	0.42
SART1	0.42
TP53TG3B	0.42
PPFIA4	0.42
COX8A	0.419
TP53TG3	0.419
PLRG1	0.419
TSPY1	0.419
ATP1A3	0.419
HIVEP3	0.418
TP53TG3C	0.418
SLC38A7	0.418
OSBP	0.418
ATP6AP1	0.418
KRT36	0.417
ANKLE1	0.417
CACNA1A	0.416
ATXN1	0.416
ABT1	0.415
PHF2	0.415
C3	0.415
PBXIP1	0.414
SCAF1	0.414
PSMD8	0.414
RNF113A	0.414
TINF2	0.413
XAB2	0.412
ADRA1D	0.412
CASC3	0.412
TSPY8	0.411
GID4	0.411
DNTTIP2	0.411
COX7A2L	0.411
MED15	0.409
RIOK2	0.408
RILPL2	0.407
SRRM2	0.406
MMS22L	0.406
ESF1	0.406
NUP62	0.405
NARFL	0.405
RPL30	0.405
PSMA7	0.405
WDR75	0.405
CNPY3	0.405
ZNF830	0.404
TOPBP1	0.404
PPM1D	0.404
PLEKHA4	0.404
NBPF16	0.403
SLC7A6OS	0.403
TUBA8	0.403
MED14	0.403
SNRNP70	0.403
C2orf27B	0.403
FBN1	0.403
SMG1	0.402
SNRNP200	0.402
ITGA2B	0.402
PRPF8	0.401
CLCN6	0.401
RRP15	0.401
EXOSC6	0.401
MAT2A	0.4
HIST2H3D	0.4

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 1809
Expression level (log2 read counts): 3.3

Expression Distribution