GTPBP10

Gene Information

Official Symbol: GTPBP10
Official Name: GTP binding protein 10
Aliases and Previous Symbols: N/A
Entrez ID: 85865
UniProt: A4D1E9
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
QNZ 0.01μM R08 exp439	1.72
PU-H71 1μM R08 exp515	1.75
AICAR 240μM R03 exp116	1.79
Bafilomycin-A1 0.009μM R08 exp454	1.87
Cannabidiol 13μM R08 exp465	1.99
UM0125461 0.74μM R02 exp84	2.58
Oligomycin-A 2μM R00 exp25	2.69

Gene	Correlation
C12orf65	0.677
MRPL21	0.676
GFM2	0.655
NDUFAF7	0.653
MRPS34	0.648
NDUFA3	0.642
HSD17B10	0.641
QRSL1	0.636
NARS2	0.629
GFM1	0.628
MRPL23	0.625
TARS2	0.624
RPUSD4	0.622
MRPS16	0.621
NDUFB11	0.618
SCO2	0.617
PET112	0.616
MRPS5	0.615
RNASEH1	0.613
MTG1	0.612
SELRC1	0.61
MTG2	0.61
PARS2	0.609
NDUFB5	0.601
YARS2	0.597
MRPL45	0.596
MTRF1L	0.596
NDUFA2	0.594
RBFA	0.592
MRPS6	0.589
RARS2	0.589
GATC	0.589
MRPS21	0.588
LARS2	0.585
RPUSD3	0.584
NDUFAF3	0.579
FTSJ2	0.577
MRP63	0.576
C17orf89	0.575
COX16	0.574
COQ2	0.572
DARS2	0.57
AARS2	0.57
DAP3	0.569
CHCHD1	0.567
FASTKD5	0.567
PET117	0.567
WBSCR16	0.566
ACAD9	0.566
MRPL47	0.566
FASTKD2	0.563
NDUFA1	0.56
BCS1L	0.56
NDUFB6	0.56
MRPS26	0.558
MRPS25	0.558
MCAT	0.556
MTO1	0.555
EARS2	0.554
NDUFC2	0.554
NUBPL	0.553
MRPL12	0.553
POLG2	0.552
SLC25A26	0.551
TEFM	0.549
COQ7	0.549
PDSS1	0.548
NDUFS2	0.548
MRPS18A	0.547
GRSF1	0.546
METTL17	0.546
MRPS9	0.545
MRPL53	0.545
PNPT1	0.545
ECSIT	0.544
HARS2	0.544
NDUFB9	0.543
MALSU1	0.543
SARS2	0.541
VARS2	0.54
TRUB2	0.54
IBA57	0.538
ERAL1	0.537
MRPS14	0.536
MRPS22	0.536
COQ3	0.53
POLG	0.53
ATP5SL	0.53
MIPEP	0.528
TIMMDC1	0.526
C1QBP	0.525
MRPL20	0.525
DDX28	0.524
MRPL55	0.523
TOMM20	0.522
TIMM8B	0.521
SUPV3L1	0.521
KIAA0391	0.52
CARS2	0.517
MRPL15	0.517
HMGXB3	0.516
NDUFA11	0.516
NDUFA10	0.515
MRPS2	0.514
MRPL44	0.514
MRPL22	0.512
WARS2	0.511
RNMTL1	0.511
POLRMT	0.51
MRPL3	0.508
TOMM6	0.508
MRPS10	0.507
MRPS23	0.507
COX11	0.506
GTPBP6	0.504
COA3	0.504
C10orf2	0.504
NDUFB3	0.503
MRPS24	0.503
TUFM	0.501
TMEM242	0.501
MTPAP	0.5
MTERFD2	0.499
RTN4IP1	0.498
NDUFAF5	0.496
DHX30	0.494
MTIF3	0.493
TFB1M	0.492
SSBP1	0.492
NDUFV1	0.492
COX6C	0.491
COA6	0.491
NDUFAF1	0.49
MTIF2	0.488
MRPL4	0.486
MARS2	0.486
MRPS12	0.485
GLRX5	0.484
FOXRED1	0.483
MRPS11	0.482
GTPBP8	0.481
NDUFAF4	0.481
MRPL41	0.48
NDUFS5	0.479
MTRF1	0.479
MRPL43	0.479
NDUFC1	0.478
DNLZ	0.476
NDUFA6	0.476
TMEM261	0.474
NSUN4	0.473
MRPL2	0.472
ATP5C1	0.472
NDUFS7	0.472
FARS2	0.471
AIFM1	0.469
MRPL18	0.468
ICT1	0.468
PITRM1	0.468
MRPL36	0.466
MRPL11	0.464
TOMM40	0.464
NDUFB10	0.463
AASDHPPT	0.463
MRPL33	0.462
MRPS33	0.461
ANGEL2	0.46
TIMM17A	0.46
NDUFB2	0.459
MTERFD1	0.457
COX7B	0.454
MRPS7	0.454
UQCRC2	0.453
NOA1	0.453
ISCA2	0.452
MRPS35	0.451
NDUFS8	0.449
COA5	0.446
MRPS17	0.445
PGM3	0.445
NFU1	0.444
COX15	0.443
NDUFA8	0.441
COX5A	0.441
UQCR10	0.439
CLPP	0.438
CHCHD4	0.436
ATP5A1	0.436
NDUFB7	0.435
MRPL1	0.435
HIGD2A	0.434
NDUFAF6	0.431
ATP5D	0.431
MRPL13	0.43
SLC25A3	0.43
ATP5H	0.43
UQCC2	0.429
SFXN4	0.428
PTCD3	0.427
OPA1	0.426
MRPL34	0.423
NDUFV2	0.422
COX20	0.422
MRPL39	0.422
MRPL28	0.422
TFAM	0.421
MRPL38	0.42
AK3	0.419
ALKBH1	0.417
MRPL42	0.416
MRPL46	0.415
MRPS18B	0.413
COQ6	0.412
COX17	0.412
TPK1	0.411
NDUFB1	0.41
TRIAP1	0.41
PREPL	0.41
FASTKD1	0.41
ALAS1	0.409
MRPL49	0.408
MRPL17	0.407
ALDH18A1	0.406
MRPL48	0.403
ATP5B	0.402

Global Fraction of Cell Lines Where Essential: 3/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	1/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 2068
Expression level (log2 read counts): 5.34

Expression Distribution