MRPS18A

Gene Information

Official Symbol: MRPS18A
Official Name: mitochondrial ribosomal protein S18A
Aliases and Previous Symbols: N/A
Entrez ID: 55168
UniProt: Q9NVS2
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
GW501516 25μM R06 exp285	-1.92
Milciclib 2μM R08 exp502	1.71
Hippuristanol 0.12μM R08 exp488	1.87
CB-5083 0.4μM R08 exp468	1.99
Aphidicolin 0.4μM R08 exp440	2.07
Torin1 0.08μM R02 exp82	2.14
ONC212 0.15μM R08 exp513	2.2
UM0125461 0.74μM R02 exp84	2.22
Monensin 0.3μM R08 exp507	2.27
Hydroxyurea 100μM R07 exp329	2.64
Thimerosal 0.85μM R08 exp529	2.67
GSK-J4 1.5μM R08 exp441	3.31

Gene	Correlation
MRPL21	0.686
MRPS34	0.684
HSD17B10	0.673
MRPS6	0.672
MRPL23	0.671
KIAA0391	0.668
VARS2	0.657
SUPV3L1	0.649
MRPS16	0.649
TARS2	0.647
MRPS21	0.638
MRP63	0.636
YARS2	0.635
RPUSD4	0.635
MRPS14	0.63
SELRC1	0.63
DAP3	0.625
FASTKD5	0.624
RBFA	0.622
MRPS5	0.621
MRPS9	0.619
MRPL47	0.616
COX16	0.616
GFM1	0.61
SARS2	0.609
MRPL53	0.605
NARS2	0.6
TRUB2	0.593
DARS2	0.589
MRPL12	0.585
TEFM	0.584
SCO2	0.583
MRPS26	0.582
MRPL18	0.58
QRSL1	0.579
EARS2	0.57
NDUFA3	0.569
MRPL15	0.568
PARS2	0.563
MRPS2	0.561
MRPL33	0.56
MTPAP	0.56
UQCRC2	0.56
MRPS24	0.559
GATC	0.559
MRPL55	0.555
TUFM	0.555
HARS2	0.552
SLC25A26	0.552
C10orf2	0.55
COA3	0.549
MRPS25	0.547
GTPBP10	0.547
MRPL3	0.544
TFAM	0.543
RARS2	0.542
MRPS10	0.541
MRPS12	0.539
FARS2	0.537
PDSS1	0.534
PET112	0.533
WBSCR16	0.532
COQ3	0.527
COX7B	0.527
NDUFB11	0.525
UQCR10	0.524
CHCHD4	0.523
C12orf65	0.522
MTG2	0.522
RNASEH1	0.521
ELAC2	0.521
BCS1L	0.519
MRPS35	0.515
NDUFAF7	0.514
MARS2	0.513
DNLZ	0.509
TRIAP1	0.507
MRPL20	0.505
MRPS23	0.503
COX15	0.503
COA6	0.501
DHRSX	0.5
MRPL44	0.496
MRPS11	0.496
COX6C	0.495
TMEM126B	0.493
MRPL52	0.492
GFM2	0.491
DHX30	0.489
PNPT1	0.489
LARS2	0.489
MRPL42	0.489
MRPS33	0.486
FTSJ2	0.485
LRPPRC	0.484
MRPL41	0.484
MRPL36	0.484
TMEM242	0.482
MRPL43	0.481
PGM3	0.481
ATP5D	0.479
TOMM20	0.476
MRPS7	0.475
COQ2	0.474
CRLS1	0.474
AARS2	0.472
TIMM8B	0.471
AASDHPPT	0.47
ATP5A1	0.467
COA5	0.465
HCCS	0.463
MRPL34	0.462
MTIF3	0.461
WARS2	0.461
MRPL45	0.461
MRPL11	0.461
MTRF1L	0.46
TPK1	0.46
MIPEP	0.458
TAMM41	0.458
MRPL13	0.458
NDUFAF4	0.457
MRPL4	0.457
MRPS22	0.457
C17orf89	0.456
TFB2M	0.456
POLG2	0.454
COX17	0.453
MTG1	0.453
NDUFA2	0.453
TAZ	0.453
RPIA	0.452
IBA57	0.45
POLG	0.45
PMM2	0.45
OPA1	0.45
MTERFD2	0.449
POLRMT	0.449
MRPS17	0.447
ATP5C1	0.446
NDUFC2	0.445
MRPL28	0.445
DDX28	0.445
NDUFB6	0.443
AIFM1	0.443
ROMO1	0.441
FASTKD1	0.44
NDUFB5	0.44
NDUFAF3	0.439
PET117	0.438
MRPL17	0.438
MRPL27	0.437
METTL17	0.437
PPA2	0.436
CYCS	0.435
GTPBP6	0.435
COX6B1	0.435
ATP5B	0.433
NDUFV1	0.433
PTCD3	0.433
TOMM40	0.432
PTRHD1	0.431
MRPL32	0.429
PPCS	0.428
CARS2	0.427
NDUFB1	0.425
TRMT61A	0.425
UQCRQ	0.425
MRPL39	0.424
DPAGT1	0.421
LSM10	0.421
THG1L	0.42
RPUSD3	0.419
TOMM22	0.419
MRPL37	0.418
RPE	0.415
ATXN10	0.412
RNMTL1	0.412
PGGT1B	0.412
SSB	0.412
MRPL22	0.411
UAP1	0.41
MBTPS2	0.41
UHRF1	0.409
NDUFA1	0.409
VEZT	0.409
MRPL38	0.408
COX10	0.408
SEC62	0.407
MRPL35	0.406
TRMT10C	0.406
ALG6	0.406
ALG8	0.404
COX11	0.403
HIGD2A	0.403
NDUFB9	0.403
PITRM1	0.402
ALG1	0.401
MRPL46	0.401
CLPP	0.4

Global Fraction of Cell Lines Where Essential: 11/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	2/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	1/21
liver	1/20
lung	4/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 775
Expression level (log2 read counts): 3.2

Expression Distribution