CBWD3

Gene Information

Official Symbol: CBWD3
Official Name: COBW domain containing 3
Aliases and Previous Symbols: N/A
Entrez ID: 445571
UniProt: Q5JTY5
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Atovaquone 15μM R08 exp451	-1.88
Docetaxel 0.001 to 0.002μM on day4 R04 exp159	1.72
Vinorelbine 0.001μM R05 exp249	1.86
A-769662 20μM R07 exp331	1.88

Gene	Correlation
CHD4	0.625
C1QTNF9B	0.611
RPS2	0.598
TBC1D3G	0.582
TBC1D3H	0.581
TCEB3CL2	0.578
NPIPB5	0.577
TWISTNB	0.571
PSMB4	0.568
ORC1	0.565
TFIP11	0.563
DTL	0.562
C14orf93	0.561
SUPT5H	0.56
TICRR	0.559
MT1E	0.557
TBC1D3F	0.554
KCTD17	0.548
EXOSC9	0.544
GOLGA6L3	0.544
PSMB2	0.543
TCEB3CL	0.543
DDTL	0.542
TCEB3C	0.541
SUPT6H	0.541
TBC1D3C	0.537
NUPL1	0.536
BYSL	0.536
SSH2	0.536
ANKLE2	0.531
DISP2	0.528
COPG1	0.528
LRR1	0.527
RNPC3	0.526
CDC45	0.526
IK	0.526
MED14	0.526
CCNA2	0.525
STIL	0.524
MED17	0.523
SLC4A1	0.523
POLR2D	0.522
TBC1D3	0.521
CEP192	0.521
LAD1	0.519
GOLGA6L4	0.518
PCF11	0.516
VASN	0.516
PSMA7	0.51
SLC38A7	0.51
RAD21	0.509
HIVEP3	0.508
COPE	0.508
AAMP	0.508
PDE4DIP	0.505
SNRPA1	0.505
UPF1	0.503
RPL35	0.503
CDC6	0.502
MYO1H	0.501
RBBP5	0.501
WDR75	0.501
NUP160	0.498
MYB	0.497
RANBP2	0.497
TYMS	0.495
TBC1D3I	0.494
TBC1D3E	0.494
POLA1	0.493
TBC1D3L	0.493
TBC1D3K	0.493
POLE	0.491
ZNF830	0.491
PSMA6	0.49
CCDC64B	0.49
GOLGA8O	0.49
WDR87	0.489
PSMD3	0.487
DDX56	0.487
COPB1	0.487
GOSR2	0.486
MED29	0.484
NBPF10	0.484
EXOSC5	0.483
CTAGE4	0.483
RRP7A	0.482
RNF121	0.482
COPB2	0.482
XAB2	0.482
HIST2H2BF	0.481
OGFR	0.48
CTAGE9	0.48
PSMC2	0.479
CHAF1A	0.479
RPS19BP1	0.479
CHCHD3	0.478
SMG1	0.478
COPZ1	0.478
PAN2	0.478
RPS28	0.477
ZFAND5	0.477
PLK4	0.477
RPS5	0.477
TP53TG3	0.476
TP53TG3B	0.476
TP53TG3C	0.475
TIMELESS	0.473
MYH2	0.472
PSMC1	0.471
AATF	0.471
NUMA1	0.47
ATP6V1C1	0.47
RPS12	0.47
PWP2	0.469
SEC13	0.468
NOP16	0.468
PAN3	0.468
POLA2	0.467
CCDC116	0.466
ORC6	0.466
SLC6A17	0.466
RAD51	0.466
PSMD6	0.465
FCN2	0.465
RRN3	0.465
PSMB1	0.465
SF3A1	0.464
OR10G3	0.464
PSMD11	0.464
OSBP	0.463
NSF	0.462
SAP30BP	0.462
TSG101	0.462
UQCRH	0.461
NUP133	0.46
CACTIN	0.46
SMG7	0.46
DNTTIP2	0.459
UTP3	0.459
VPS54	0.459
MED15	0.457
C2orf27B	0.457
NAPA	0.457
RPL34	0.457
WDR43	0.456
PLK1	0.455
AQR	0.454
POLR2F	0.454
ATP13A1	0.454
ARCN1	0.454
RRP15	0.454
NFATC4	0.453
KIF3C	0.452
AAAS	0.452
KRT78	0.452
RPS7	0.452
HIST2H3C	0.451
FAM231C	0.451
FAM231A	0.451
HIST2H3A	0.451
SYT9	0.45
HNRNPC	0.45
GID4	0.45
COPA	0.45
ACSF2	0.449
MDM2	0.449
ATP6V1A	0.449
RIOK2	0.448
IGFN1	0.448
ATP6V0C	0.448
DDT	0.447
HAP1	0.447
PSMC6	0.446
NUP153	0.446
MSH5	0.446
CGB2	0.445
PIGS	0.445
PSMC5	0.445
CDCA3	0.445
GOLGA6A	0.444
FBXW9	0.444
S1PR4	0.444
POLR1A	0.443
TP53TG3D	0.443
NUP205	0.443
SART1	0.442
TSPY1	0.441
UTP20	0.441
NOL10	0.44
ZNF655	0.44
TSPY8	0.439
FAM160A1	0.439
PSMD2	0.438
NARFL	0.437
HIST2H3D	0.437
GOLGA6L6	0.436
RBM39	0.436
SCGB1C1	0.436
SCAF1	0.435
EIF4A3	0.435
COL2A1	0.435
TOP1MT	0.435
UBAP1	0.434
NUP107	0.433
RILPL2	0.433
NUP85	0.432
KPNB1	0.432
HNRNPA1	0.432
ANKLE1	0.432
AKT1S1	0.432
ELMOD3	0.431
PLA2G4F	0.431
RPSA	0.431
PPIE	0.431
ZNF106	0.43
TRAIP	0.429
DDX47	0.429
GOLGA6L1	0.429
SF3A3	0.429
HIST1H2BE	0.429
NPIPB8	0.429
CWC22	0.428
MYT1L	0.428
TRAPPC11	0.428
VPS28	0.428
PSAP	0.427
RPS19	0.426
RFXANK	0.426
GOLGA8J	0.426
CHMP2A	0.426
RPL14	0.426
RPL6	0.425
PBXIP1	0.425
ATP6AP1	0.424
MADCAM1	0.424
INTS5	0.422
SH3BP1	0.422
ZNF541	0.421
CDC73	0.42
RPS3A	0.42
SRRM2	0.42
KRT2	0.42
WDR46	0.42
ISCU	0.419
FBN1	0.419
DOCK6	0.419
CLASP1	0.418
MORC2	0.418
SF3A2	0.418
SNIP1	0.418
PSMD7	0.418
APRT	0.418
TONSL	0.417
HIST1H4B	0.416
PAF1	0.416
PPFIA4	0.415
TTC1	0.415
PSMD1	0.415
PSMB3	0.415
RPL9	0.414
NUP98	0.413
SSRP1	0.412
AKIRIN2	0.411
CHMP4B	0.411
SYS1	0.41
GBF1	0.41
MFSD12	0.41
LIPE	0.409
TSR1	0.409
MBTD1	0.409
AHCTF1	0.409
NBPF16	0.408
CCDC94	0.407
GAR1	0.407
FAM20A	0.407
CDT1	0.407
SFPQ	0.407
LOC643669	0.406
POLD3	0.406
UBL5	0.405
GPRIN2	0.405
EGR2	0.405
NUP43	0.404
RPS9	0.404
TPX2	0.404
CMYA5	0.403
PDCD11	0.402
COX8A	0.402
RRM1	0.402
DDX21	0.401
ZNF574	0.401
FAM25B	0.401
SRRT	0.401
TOPBP1	0.401
USP35	0.4
MCOLN1	0.4
EBNA1BP2	0.4
ATP6AP2	0.4
NDC1	0.4
RPL30	0.4
CEBPZ	0.4
POLR2L	0.4

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	1/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 1497
Expression level (log2 read counts): 5.84

Expression Distribution