SLC25A26

Gene Information
  • Official Symbol: SLC25A26
  • Official Name: solute carrier family 25 member 26
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 115286
  • UniProt: Q70HW3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene is a member of the mitochondrial carrier family which includes nuclear-encoded transporters localized on the inner mitochondrial membranes. Members of the family transport important small molecules across the mitochondrial inner membrane. This protein is involved in the transport of S-adenosylmethionine (SAM) into the mitochondria. Mutations in this gene are associated with combined oxidative phosphorylation deficiency 28. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2017].
  • UniProt Summary: Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S- adenosylmethionine (SAM) into the mitochondria. {ECO:0000269|PubMed:14674884, ECO:0000269|PubMed:26522469}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1108
  • Expression level (log2 read counts): 5.2

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1