VASN

Gene Information

Official Symbol: VASN
Official Name: vasorin
Aliases and Previous Symbols: N/A
Entrez ID: 114990
UniProt: Q6EMK4
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: May act as an inhibitor of TGF-beta signaling. {ECO:0000269|PubMed:15247411}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Milciclib 2μM R08 exp502	-2.01
Oligomycin-A 20μM R00 exp26	-1.82
Tanespimycin 14μM R08 exp527	-1.78
Losmapimod 1μM R07 exp376	1.78
BRD2 inhibitor II 20μM R07 exp341	1.86
Colchicine 0.009μM R05 exp215	2.11
Epothilone-D 0.004 to 0.006μM on day4 R05 exp232	2.15
Cycloheximide 0.2μM R00 exp15	2.22

Gene	Correlation
COPE	0.622
C14orf93	0.622
C1QTNF9B	0.609
PAN3	0.598
PSMD1	0.588
MT1E	0.585
TCEB3CL2	0.585
TBC1D3H	0.582
ORC1	0.581
TBC1D3G	0.581
TICRR	0.581
TBC1D3F	0.581
TCEB3C	0.579
CDC73	0.575
TBC1D3C	0.574
TWISTNB	0.571
CHD4	0.565
TBC1D3	0.563
TFIP11	0.561
PSMD11	0.559
KCTD17	0.557
TBC1D3K	0.553
TBC1D3E	0.553
PSMD3	0.553
TBC1D3L	0.553
TBC1D3I	0.552
RPS2	0.552
OGFR	0.551
SUPT6H	0.548
PSMA6	0.546
CCDC64B	0.545
CCNA2	0.544
TCEB3CL	0.543
ZFAND5	0.542
COPG1	0.541
RBM39	0.541
AAMP	0.539
DTL	0.538
PAN2	0.536
NUP54	0.536
CHAF1A	0.535
NARFL	0.534
NUPL1	0.531
SCAF1	0.531
CDCA3	0.53
NUP160	0.529
MYO1H	0.529
ORC6	0.528
PSMB4	0.528
SF3A3	0.527
CGB2	0.527
RPS12	0.526
CEP192	0.525
SFPQ	0.524
NOL10	0.524
SMG7	0.523
PAF1	0.523
HAP1	0.522
AHCTF1	0.52
AQR	0.519
PSMD14	0.518
SUPT5H	0.516
CBWD3	0.516
GOLGA6A	0.516
PSMD6	0.516
POLA2	0.516
KPNB1	0.515
COPA	0.515
SF3A1	0.513
DDTL	0.512
RPS9	0.512
PSMC2	0.511
RFXANK	0.51
PSMB2	0.509
LRR1	0.509
ATXN1	0.508
CKAP5	0.508
ZNF106	0.508
EXOSC9	0.506
PRPF8	0.506
RPSA	0.505
NUP133	0.505
GAR1	0.504
GOLGA8O	0.503
STIL	0.502
TERF2	0.502
KRT78	0.501
SNRPA1	0.5
RPS3A	0.499
RPS28	0.499
PSMC1	0.497
EIF4A3	0.497
CMYA5	0.496
CBWD5	0.495
PSAP	0.495
HIST1H2BE	0.495
ELMOD3	0.493
CWC22	0.493
WDR87	0.491
SMG1	0.491
NPIPB5	0.491
KIF3C	0.49
ARCN1	0.49
AKIRIN2	0.488
PSMC6	0.487
POLA1	0.485
FAM86B2	0.485
DISP2	0.485
TTYH1	0.485
SYT9	0.485
RRN3	0.485
HIST2H3A	0.483
MDM2	0.483
NUP205	0.482
PSMB3	0.482
RBBP5	0.482
HIST2H3C	0.482
CBWD6	0.482
MADCAM1	0.482
RPL35	0.481
EGR2	0.48
POLR1A	0.48
MED17	0.479
PSMD7	0.479
TAGLN	0.478
SLC6A17	0.478
ABHD8	0.478
IK	0.476
HIST1H4B	0.476
PWP2	0.476
CDC6	0.476
COX8A	0.476
SLC4A1	0.476
SSH2	0.475
ISCU	0.475
RIOK2	0.474
TUBA8	0.473
FAM160A1	0.473
RAD51	0.472
PLK1	0.472
RAD21	0.471
FCN2	0.47
CNPY3	0.47
FBXO5	0.469
COL2A1	0.469
S1PR4	0.468
VPS54	0.468
LOC643669	0.467
PIGS	0.467
TRA2B	0.467
SAP30BP	0.466
SNRNP200	0.466
MYT1L	0.466
GNB3	0.466
RRP7A	0.465
ZNF655	0.465
RPS14	0.465
RPL30	0.465
RPS19BP1	0.464
MYLK3	0.464
CLN6	0.464
KIAA0947	0.464
ANKLE2	0.464
SF3B3	0.463
NOP16	0.463
IGFN1	0.463
PARP3	0.462
CNOT1	0.462
CDC45	0.462
DOCK6	0.461
NBPF16	0.461
DIDO1	0.461
ANKLE1	0.461
OR10G3	0.46
PDE4DIP	0.46
SEC13	0.46
ATP6V1C1	0.46
TERF1	0.459
PSMC3	0.459
NAPA	0.458
NUP155	0.457
RPS5	0.457
DNTTIP2	0.457
XYLT2	0.456
SNRNP70	0.456
HNRNPC	0.455
CCT4	0.455
NFATC4	0.455
HNRNPA1	0.455
SNIP1	0.454
NUP85	0.454
MSH5	0.452
INTS5	0.452
UQCRH	0.452
HIST2H2BF	0.452
CCDC94	0.451
AAAS	0.451
UBAP1	0.451
SPRR2B	0.451
RRP15	0.45
HIVEP3	0.449
NUP62	0.449
CHMP2A	0.448
MYH2	0.448
COPB2	0.448
DNM2	0.448
COPB1	0.447
BYSL	0.447
MED12	0.447
ADRM1	0.446
TRIM52	0.445
RPS7	0.445
RPL7L1	0.445
UTP20	0.444
ALDH1B1	0.444
TPX2	0.444
UTP3	0.444
ARHGEF35	0.444
EXOSC5	0.444
CTR9	0.443
FAM25B	0.443
TRAIP	0.442
POLR2F	0.441
ACSF2	0.441
ZNF219	0.44
NDC1	0.439
RPS19	0.439
RPL14	0.438
RNPC3	0.438
RPLP1	0.437
DYNC1I2	0.437
NUP153	0.437
GPRIN2	0.437
NPIPB8	0.437
PSMC5	0.437
PPFIA4	0.436
RPL6	0.435
GID4	0.435
MED29	0.435
USP35	0.434
DDX56	0.434
RPL7A	0.434
POLE	0.433
PCF11	0.432
NUP43	0.432
ATP6V0C	0.432
ITGA2B	0.431
PSMA7	0.431
NBPF10	0.431
PBXIP1	0.431
GON4L	0.43
POLI	0.43
WDR43	0.429
POLR2A	0.427
PSMD2	0.426
RFC1	0.426
UPF1	0.426
SPRR2A	0.425
NUFIP2	0.425
TIMELESS	0.425
NDC80	0.425
RILPL2	0.425
MMS22L	0.424
PRKCZ	0.424
SART1	0.424
RPS3	0.424
CACTIN	0.423
TP53TG3B	0.423
LAD1	0.423
TP53TG3C	0.422
MFSD12	0.422
CCDC116	0.422
TP53TG3	0.422
PLA2G4F	0.422
TOP1MT	0.421
COPZ1	0.421
RPL34	0.421
MYB	0.421
GOLGA8J	0.42
MBTD1	0.42
RPL8	0.42
AKT1S1	0.419
FBXW9	0.419
UBE2Q2L	0.419
TONSL	0.418
LIPE	0.418
ABT1	0.418
VPS28	0.417
TSG101	0.417
NOL12	0.417
RAN	0.416
CRNKL1	0.416
GOSR2	0.416
UBL5	0.416
RILPL1	0.415
BID	0.415
RANBP2	0.414
RPS20	0.414
CLPTM1	0.413
SH3BP1	0.412
SULT1A3	0.412
SULT1A4	0.412
SLC38A7	0.412
ZNF830	0.412
INO80E	0.411
PSMB1	0.411
NUP93	0.411
USP36	0.411
NUP107	0.41
HIST2H3D	0.41
NOTCH2	0.41
EXD1	0.41
ADRA1D	0.41
RNF113A	0.409
SRRM2	0.408
PLK4	0.408
C2orf27B	0.407
SHPK	0.407
POLR2D	0.407
DDX21	0.407
OR11H6	0.406
CAST	0.406
NCAPG	0.406
GOLGA6B	0.405
IL1B	0.405
HINFP	0.405
TYMS	0.405
PNO1	0.405
NSF	0.404
FDX1L	0.404
CACNA1A	0.404
POLR2J3	0.402
GOLGA6L3	0.402
BCL2L1	0.402
BRD2	0.402
RNF4	0.402
MYO18A	0.401
C3	0.4

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 1295
Expression level (log2 read counts): 0.55

Expression Distribution